Bioinformatics approaches for translational medicine
What are the genetic differences between healthy and diseased cells.
Dba -> RNA -> Protein
Mutations can occur during this progression. Changes in rna can change the concentration of protein.
Using SNP chips to detect variations on DNA.
Protein expression via mass spectrometry. By analyzing weight different proteins can be identified.
Some in individual cases but the network effects of millions of elements creates amazing complexity.
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